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Efficacy and Safety of Modafinil (Provigil) for the Treatment of Fatigue in Multiple Sclerosis: A Two Centre Phase 2 Study JNNP 72:179-183,150, Rammohan,K.W.,et al, 2002 See this aricle in Pubmed Article Abstract These data suggest that 200 mg/day modafinil significantly improves fatigue and is well tolerated in patients with MS.

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